An experimental approach to probe conformational changes in proteinstructure using a biotin derivative followed by mass spectrometry

The biotinylation patterns of two soluble model proteins (BSA and CA II) were analyzed under different conditions. In a first step these proteins were biotinylated with an increasing molar excess of a biotin derivative. In this case increases in biotin concentration led to an increase in the number...

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主要作者:	Azimzadeh, Omid
其他作者:	Lingelbach, Klaus (Prof. Dr. ) (BetreuerIn (Doktorarbeit))
格式:	Dissertation
語言:	英语
出版:	Philipps-Universität Marburg 2008
主題:	Plasmodium falciparum Conformational changes Konformationsänderung Bovines Serum Albumin Biotinylation Bovine serum albumin Massenspektrometrie Biowissenschaften, Biologie Biotinylierung Mass spectrometry Life sciences
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