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An experimental approach to probe conformational changes in proteinstructure using a biotin derivative followed by mass spectrometry
The biotinylation patterns of two soluble model proteins (BSA and CA II) were analyzed under different conditions. In a first step these proteins were biotinylated with an increasing molar excess of a biotin derivative. In this case increases in biotin concentration led to an increase in the number...
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| Format: | Doctoral Thesis |
| Language: | English |
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Philipps-Universität Marburg
2008
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| Online Access: | PDF Full Text |
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