An experimental approach to probe conformational changes in proteinstructure using a biotin derivative followed by mass spectrometry

An experimental approach to probe conformational changes in proteinstructure using a biotin derivative followed by mass spectrometry

The biotinylation patterns of two soluble model proteins (BSA and CA II) were analyzed under different conditions. In a first step these proteins were biotinylated with an increasing molar excess of a biotin derivative. In this case increases in biotin concentration led to an increase in the number...

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Bibliographische Detailangaben
1. Verfasser: Azimzadeh, Omid
Beteiligte: Lingelbach, Klaus (Prof. Dr. ) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2008
Schlagworte:
Plasmodium falciparum
Biotinylation
Konformationsänderung
Bovines Serum Albumin
Massenspektrometrie
Conformational changes
Biowissenschaften, Biologie
Mass spectrometry
Bovine serum albumin
Biotinylierung
Life sciences
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