An experimental approach to probe conformational changes in proteinstructure using a biotin derivative followed by mass spectrometry

The biotinylation patterns of two soluble model proteins (BSA and CA II) were analyzed under different conditions. In a first step these proteins were biotinylated with an increasing molar excess of a biotin derivative. In this case increases in biotin concentration led to an increase in the number...

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Bibliographic Details
Main Author: Azimzadeh, Omid
Contributors: Lingelbach, Klaus (Prof. Dr. ) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2008
Online Access:PDF Full Text
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