Partial p53 reactivation is sufficient to induce cancer regression
Impaired p53 function is one of the central molecular features of a tumor cell and even a partial reduction in p53 activity can increase the cancer risk in mice and men. From a therapeutic perspective it is noteworthy that tumor cells often become addicted to the absence of p53 providing a rationale...
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Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
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Philipps-Universität Marburg
2022
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Online Access: | PDF Full Text |
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urn:nbn:de:hebis:04-es2023-01215 |
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Publication Date: |
2023-09-04 |
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Erstveröffentlichung: Klimovich, B., Meyer, L., Merle, N. et al. Partial p53 reactivation is sufficient to induce cancer regression. J Exp Clin Cancer Res 41, 80 (2022). https://doi.org/10.1186/s13046-022-02269-6 |
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79 (2024), 11 (2023) |
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https://creativecommons.org/licenses/by/4.0 |
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https://archiv.ub.uni-marburg.de/es/2023/0121 https://doi.org/10.1186/s13046-022-02269-6 |