Toward Novel [18F]Fluorine-labeled Radiotracers for the Imaging of α-Synuclein Fibrils

The accumulation of α-synuclein aggregates (α-syn) in the human brain is an occurrence common to all α-synucleinopathies. Non-invasive detection of these aggregates in a living brain with a target-specific radiotracer is not yet possible. We have recently discovered that the inclusion of a methylene...

Ausführliche Beschreibung

Bibliographische Detailangaben

Autoren:	Uzuegbunam, Bright C., Li, Junhao, Paslawsk, Wojciech, Weber, Wolfgang, Svenningsson, Per, Ågren, Hans, Yousefi, Behrooz Hooshyar
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2022
Schlagworte:	PET tracer development α-synuclein aggregates disaryl Medizin positron emission tomography (PET) ruthenium-mediated deoxyfluorination α-synucleinopathies Medical sciences Medicine
Online-Zugang:	PDF-Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!