Toward Novel [18F]Fluorine-labeled Radiotracers for the Imaging of α-Synuclein Fibrils

Uzuegbunam, Bright C.; Li, Junhao; Paslawsk, Wojciech; Weber, Wolfgang; Svenningsson, Per; Ågren, Hans; Yousefi, Behrooz Hooshyar

Toward Novel [18F]Fluorine-labeled Radiotracers for the Imaging of α-Synuclein Fibrils

The accumulation of α-synuclein aggregates (α-syn) in the human brain is an occurrence common to all α-synucleinopathies. Non-invasive detection of these aggregates in a living brain with a target-specific radiotracer is not yet possible. We have recently discovered that the inclusion of a methylene...

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Автори:	Uzuegbunam, Bright C., Li, Junhao, Paslawsk, Wojciech, Weber, Wolfgang, Svenningsson, Per, Ågren, Hans, Yousefi, Behrooz Hooshyar
Формат:	Стаття
Мова:	англійська
Опубліковано:	Philipps-Universität Marburg 2022
Предмети:	PET tracer development disaryl Medizin positron emission tomography (PET) α-synucleinopathies α-synuclein aggregates ruthenium-mediated deoxyfluorination Medical sciences Medicine
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Toward Novel [18F]Fluorine-labeled Radiotracers for the Imaging of α-Synuclein Fibrils

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