Toward Novel [18F]Fluorine-labeled Radiotracers for the Imaging of α-Synuclein Fibrils

Toward Novel [18F]Fluorine-labeled Radiotracers for the Imaging of α-Synuclein Fibrils

The accumulation of α-synuclein aggregates (α-syn) in the human brain is an occurrence common to all α-synucleinopathies. Non-invasive detection of these aggregates in a living brain with a target-specific radiotracer is not yet possible. We have recently discovered that the inclusion of a methylene...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Uzuegbunam, Bright C., Li, Junhao, Paslawsk, Wojciech, Weber, Wolfgang, Svenningsson, Per, Ågren, Hans, Yousefi, Behrooz Hooshyar
Natura: Articolo
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2022
Soggetti:
PET tracer development
disaryl
Medizin
positron emission tomography (PET)
α-synucleinopathies
α-synuclein aggregates
ruthenium-mediated deoxyfluorination
Medical sciences Medicine
Accesso online:PDF Full Text
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
No references were found for this record.

Documenti analoghi