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Remodelling regulates the heterochromatin of retrotransposons in mouse embryonic stem cells

Chromatin remodellers slide, assemble, eject or edit nucleosomes influencing chromatin structure, DNA accessibility and transcriptional programmes. The SNF2-like remodeller SMARCAD1 is conserved from yeast to human cells and is highly expressed in mouse embryonic stem cells. Upon its loss cells lose...

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Autor principal: Sachs, Parysatis
Altres autors: Mermoud, Jacqueline (Dr.) (Assessor de tesis)
Format: Dissertation
Idioma:anglès
Publicat: Philipps-Universität Marburg 2021
Matèries:
SMARCAD1
Medizin
Chromatin remodelling in stem cells
Chromatin in Stammzellen
ERVs
ERV
stem cells
Remodelling
ES cells
retrotransposons
repression
Chromatin
KAP1
Medical sciences Medicine
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Signatura: urn:nbn:de:hebis:04-z2021-01974
Data de publicació: 2021-06-08
Datum der Annahme: 2021-04-21
Downloads: 31 (2025), 129 (2024), 110 (2023), 140 (2022), 95 (2021)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL d'accés: https://archiv.ub.uni-marburg.de/diss/z2021/0197
https://doi.org/10.17192/z2021.0197

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