Remodelling regulates the heterochromatin of retrotransposons in mouse embryonic stem cells

Chromatin remodellers slide, assemble, eject or edit nucleosomes influencing chromatin structure, DNA accessibility and transcriptional programmes. The SNF2-like remodeller SMARCAD1 is conserved from yeast to human cells and is highly expressed in mouse embryonic stem cells. Upon its loss cells lose...

Full description

Bibliographic Details

Main Author:	Sachs, Parysatis
Contributors:	Mermoud, Jacqueline (Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2021
Subjects:	SMARCAD1 Medizin Chromatin remodelling in stem cells Chromatin in Stammzellen ERVs ERV stem cells Remodelling ES cells retrotransposons repression Chromatin KAP1 Medical sciences Medicine
Online Access:	PDF Full Text
Tags:	Add Tag No Tags, Be the first to tag this record!