Regulation of Rho-activating proteins by heterotrimeric G proteins: Sensitivity of Gα RhoGEF interaction is determined by dissociation kinetics

Activation of RhoGTPases downstream of G protein coupled receptors is important for many physiological functions, such as blood pressure regulation. The subfamilies Rho, Rac and Cdc42 are the best understood RhoGTPases and the present study focused on signaling towards the Rho subfamily member RhoA....

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Bibliografski detalji

Glavni autor:	Bodmann, Eva-Lisa
Daljnji autori:	Bünemann, Moritz (Prof.) (Savjetnik disertacije)
Format:	Dissertation
Jezik:	engleski
Izdano:	Philipps-Universität Marburg 2014
Teme:	Gα13 Gαq Biowissenschaften, Biologie Regulator of G protein signaling 2 p63RhoGEF Förster resonance energy transfer Fluoreszenz-Resonanz-Energie-Transfer leukemia-associated RhoGEF G-Protein gekoppelte Rezeptoren Leukämie assoziiertes RhoGEF Life sciences
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