Regulation of Rho-activating proteins by heterotrimeric G proteins: Sensitivity of Gα RhoGEF interaction is determined by dissociation kinetics

Activation of RhoGTPases downstream of G protein coupled receptors is important for many physiological functions, such as blood pressure regulation. The subfamilies Rho, Rac and Cdc42 are the best understood RhoGTPases and the present study focused on signaling towards the Rho subfamily member RhoA....

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Bibliographic Details
Main Author: Bodmann, Eva-Lisa
Contributors: Bünemann, Moritz (Prof.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2014
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Call Number: urn:nbn:de:hebis:04-z2014-04749
Publication Date: 2015-06-25
Date of Acceptance: 2014-11-14
Downloads: 1 (2023), 127 (2022), 93 (2021), 98 (2020), 155 (2019), 68 (2018)
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author.
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