Development of new inhibitors for the type II transmembrane serine protease matriptase

Several new inhibitors were prepared and tested as potential matriptase inhibitors. The most potent compounds were found among the tertiary amides of arylsulfonylated-3-amidinophenylalanines. The incorporation of suitable bis-substituted biphenylsulfonyl groups in combination with appropriate C-term...

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Auteur principal:	Hammami Maya
Autres auteurs:	Steinmetzer, Torsten (Prof. Dr.) (Directeur de thèse)
Format:	Dissertation
Langue:	anglais
Publié:	Philipps-Universität Marburg 2012
Sujets:	Cancer, Influenza H9N2 influenza virus Inhibitors Naturwissenschaften Serinprotease Matriptase Cancer Natural sciences & mathematics
Accès en ligne:	Texte intégral en PDF
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