Development of new inhibitors for the type II transmembrane serine protease matriptase
Several new inhibitors were prepared and tested as potential matriptase inhibitors. The most potent compounds were found among the tertiary amides of arylsulfonylated-3-amidinophenylalanines. The incorporation of suitable bis-substituted biphenylsulfonyl groups in combination with appropriate C-term...
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Format: | Doctoral Thesis |
Language: | English |
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Philipps-Universität Marburg
2012
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Online Access: | PDF Full Text |
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