Development of new inhibitors for the type II transmembrane serine protease matriptase

Several new inhibitors were prepared and tested as potential matriptase inhibitors. The most potent compounds were found among the tertiary amides of arylsulfonylated-3-amidinophenylalanines. The incorporation of suitable bis-substituted biphenylsulfonyl groups in combination with appropriate C-term...

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Bibliographic Details
Main Author: Hammami Maya
Contributors: Steinmetzer, Torsten (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2012
Subjects:
Online Access:PDF Full Text
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