Chemoenzymatic Synthesis of Chromodepsipeptides and Natural Product Discovery via Genome Mining

Recent advances in the development of sequencing technologies have enabled the identification of a multitude of bacterial gene clusters, putatively involved in the biosynthesis of nonribosomal peptides (NRPs). Peptides of nonribosomal origin constitute a class of structurally and functionally divers...

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Bibliografische gegevens

Hoofdauteur:	Robbel, Lars
Andere auteurs:	Marahiel, Mohamed (Prof. Dr.) (Thesis begeleider)
Formaat:	Dissertation
Taal:	Duits
Gepubliceerd in:	Philipps-Universität Marburg 2010
Onderwerpen:	NRPS cyclodimerization Thioesterase II Genomische Mining genome mining Chemie Modifikation <Biochemie> Acetylierung Sekundärmetabolit Genanalyse Zyklodimerisierung Hydroxylierung hydroxylation acetylation Chemistry & allied sciences
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