Identification and functional characterization of protein domains in the transcription factor TWIST

Saethre-Chotzen syndrome is an autosomal dominant inherited disorder with premature fusion of cranial sutures. It is caused by nucleotide sequence changes within or in proximity of the TWIST1 gene. This gene encodes for a bHLH transcription factor, which inhibits osteogenic differentiation by transc...

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主要作者:	Singh, Shalini
其他作者:	Kunz, Jürgen (Dr.) (BetreuerIn (Doktorarbeit))
格式:	Dissertation
语言:	英语
出版:	Philipps-Universität Marburg 2006
主题:	Transcription factor Nucleus localization signal Medizin Protein domains TWIST Medical sciences Medicine
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