Identification and functional characterization of protein domains in the transcription factor TWIST

Saethre-Chotzen syndrome is an autosomal dominant inherited disorder with premature fusion of cranial sutures. It is caused by nucleotide sequence changes within or in proximity of the TWIST1 gene. This gene encodes for a bHLH transcription factor, which inhibits osteogenic differentiation by transc...

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Bibliographic Details

Main Author:	Singh, Shalini
Contributors:	Kunz, Jürgen (Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2006
Subjects:	Nucleus localization signal Medizin Transcription factor TWIST Protein domains Medical sciences Medicine
Online Access:	PDF Full Text
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