Chemoenzymatic and Template-Directed Synthesis of Bioactive Macrocyclic Peptides
Nonribosomal peptide synthetases (NRPS) are large multienzyme complexes, which simultaneously represent template and biosynthetic machinery for the production of structurally diverse peptidic products that feature high pharmacological and biological activities. A key determinant of nonribosomal pept...
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Format: | Doctoral Thesis |
Language: | English |
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Philipps-Universität Marburg
2005
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Online Access: | PDF Full Text |
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