Chemoenzymatic and Template-Directed Synthesis of Bioactive Macrocyclic Peptides

Chemoenzymatic and Template-Directed Synthesis of Bioactive Macrocyclic Peptides

Nonribosomal peptide synthetases (NRPS) are large multienzyme complexes, which simultaneously represent template and biosynthetic machinery for the production of structurally diverse peptidic products that feature high pharmacological and biological activities. A key determinant of nonribosomal pept...

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Detaylı Bibliyografya
Yazar: Grünewald, Jan
Diğer Yazarlar: Marahiel, Mohamed (Prof.) (Tez danışmanı)
Materyal Türü: Dissertation
Dil:İngilizce
Baskı/Yayın Bilgisi: Philipps-Universität Marburg 2005
Konular:
Calcium-dependent antibiotic
Peptide cyclases
NRPS
Lipopeptide
Peptidantibiotikum
Daptomycin
Chemie
Peptidsynthetasen
Lipopeptides
Kalzium-abhängiges Antibiotikum
Peptidderivate
Zyklasen
Cyclopeptide
Chemistry & allied sciences
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