Novel Strategies for Model-Building of G Protein-Coupled Receptors

The G protein-coupled receptors constitute still the most densely populated proteinfamily encompassing numerous disease-relevant drug targets. Consequently, medicinal chemistry is expected to pursue targets from that protein family in that hits need to be generated and subsequently optimized towards...

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Detalhes bibliográficos

Autor principal:	van Neuren, Anske Stephanie
Outros Autores:	Klebe, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Formato:	Dissertation
Idioma:	inglês
Publicado em:	Philipps-Universität Marburg 2003
Assuntos:	Computational chemistry GTP-bindende Proteine Drug design G-Proteine Molekulardesign Medizin Molecular design G protein-gekuppelte Rezeptoren Ligand docking Arzneimitteldesign Membranproteine GPCR G protein coupled receptors Medical sciences Medicine
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