Novel Strategies for Model-Building of G Protein-Coupled Receptors

Novel Strategies for Model-Building of G Protein-Coupled Receptors

The G protein-coupled receptors constitute still the most densely populated proteinfamily encompassing numerous disease-relevant drug targets. Consequently, medicinal chemistry is expected to pursue targets from that protein family in that hits need to be generated and subsequently optimized towards...

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Bibliographische Detailangaben
1. Verfasser: van Neuren, Anske Stephanie
Beteiligte: Klebe, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2003
Schlagworte:
GTP-bindende Proteine
G-Proteine
Molekulardesign
Medizin
GPCR
G protein-gekuppelte Rezeptoren
Drug design
Computational chemistry
Arzneimitteldesign
Membranproteine
Molecular design
G protein coupled receptors
Ligand docking
Medical sciences Medicine
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