KLF4‑mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP
The immunoreceptor NKG2D, which is expressed on NK cells and T cell subsets is critically involved in tumor immune surveillance. This applies in particular to acute myeloid leukemia (AML), which evades immune detection by downregulation of NKG2D ligands (NKG2D-L), including MICA. The absence of NK...
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| Format: | Artikel |
| Sprache: | Englisch |
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Philipps-Universität Marburg
2023
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Online
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urn:nbn:de:hebis:04-es2024-07910 |
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| Publikationsdatum: |
2024-01-23 |
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Erstveröffentlichung: Alkhayer, R., Ponath, V., Frech, M. et al. KLF4-mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP. Cell Commun Signal 21, 94 (2023). https://doi.org/10.1186/s12964-023-01118-z |
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29 (2025), 106 (2024) |
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https://creativecommons.org/licenses/by/4.0 |
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https://archiv.ub.uni-marburg.de/es/2024/0791 https://doi.org/10.1186/s12964-023-01118-z |