KLF4‑mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP
The immunoreceptor NKG2D, which is expressed on NK cells and T cell subsets is critically involved in tumor immune surveillance. This applies in particular to acute myeloid leukemia (AML), which evades immune detection by downregulation of NKG2D ligands (NKG2D-L), including MICA. The absence of NK...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , , |
---|---|
Fformat: | Erthygl |
Iaith: | Saesneg |
Cyhoeddwyd: |
Philipps-Universität Marburg
2023
|
Pynciau: | |
Mynediad Ar-lein: | Testun PDF llawn |
Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|
Rhyngrwyd
Testun PDF llawnRhif Galw: |
urn:nbn:de:hebis:04-es2024-07910 |
---|---|
Dyddiad Cyhoeddi: |
2024-01-23 |
Ffynhonnell: |
Erstveröffentlichung: Alkhayer, R., Ponath, V., Frech, M. et al. KLF4-mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP. Cell Commun Signal 21, 94 (2023). https://doi.org/10.1186/s12964-023-01118-z |
Downloads: |
38 (2024) |
Lizenz: |
https://creativecommons.org/licenses/by/4.0 |
URL mynediad: |
https://archiv.ub.uni-marburg.de/es/2024/0791 https://doi.org/10.1186/s12964-023-01118-z |