Imaxe de Portada

Pharmacological modulation of myeloid-derived suppressor cells to dampen inflammation

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population with potent suppressive and regulative properties. MDSCs’ strong immunosuppressive potential creates new possibilities to treat chronic inflammation and autoimmune diseases or induce tolerance towards transplantation. Here,...

Descrición completa

Gardado en:
Autoren: van Geffen, Chiel, Heiss, Constantin, Deißler, Astrid, Kolahian, Saeed
Formato: Artigo
Idioma:inglés
Publicado: Philipps-Universität Marburg 2022
Schlagworte:
pharmacotherapy
inflammation
MDSC
Medizin
immunomodulation
immune suppression
Medical sciences Medicine
Acceso en liña:Texto completo PDF
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
Descripción
Zusammenfassung:Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population with potent suppressive and regulative properties. MDSCs’ strong immunosuppressive potential creates new possibilities to treat chronic inflammation and autoimmune diseases or induce tolerance towards transplantation. Here, we summarize and critically discuss different pharmacological approaches which modulate the generation, activation, and recruitment of MDSCs in vitro and in vivo, and their potential role in future immunosuppressive therapy.
descrición da copia:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
Descrición Física:26 Seiten
DOI:10.3389/fimmu.2022.933847

Títulos similares