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ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed in tumor and immune cells of the tumor microenvironm...

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Главные авторы: Cook, Lena, Sengelmann, Marie, Winkler, Birte, Nagl, Constanze, Koch, Sarah, Schlomann, Uwe, Slater, Emily P., Miller, Miles A., von Strandmann, Elke Pogge, Dörsam, Bastian, Preußer, Christian, Bartsch, Jörg W.
Формат: Статья
Язык:английский
Опубликовано: Philipps-Universität Marburg 2022
Предметы:
tumor microenvironment
MMP-9
regulation
Medizin
ADAM8
extracellular vesicles
PDAC
lipocalin 2
Medical sciences Medicine
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Шифр: urn:nbn:de:hebis:04-es2022-01557
Дата публикации: 2022-09-01
Источник: Erstveröffentlichung: Cook, L.; Sengelmann, M.; Winkler, B.; Nagl, C.; Koch, S.; Schlomann, U.; Slater, E.P.; Miller, M.A.; von Strandmann, E.P.; Dörsam, B.; Preußer, C.; Bartsch, J.W. ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9. Int. J. Mol. Sci. 2022, 23, 1976. https://doi.org/10.3390/ijms23041976
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Lizenz: https://creativecommons.org/licenses/by/4.0
Доступ через URL: https://archiv.ub.uni-marburg.de/es/2022/0155
https://doi.org/10.3390/ijms23041976

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