ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed in tumor and immune cells of the tumor microenvironm...

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Detalhes bibliográficos
Principais autores: Cook, Lena, Sengelmann, Marie, Winkler, Birte, Nagl, Constanze, Koch, Sarah, Schlomann, Uwe, Slater, Emily P., Miller, Miles A., von Strandmann, Elke Pogge, Dörsam, Bastian, Preußer, Christian, Bartsch, Jörg W.
Formato: Artigo
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2022
Assuntos:
ADAM8
lipocalin 2
MMP-9
extracellular vesicles
regulation
tumor microenvironment
Medizin
PDAC
Medical sciences Medicine
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Texto Completo em Formato PDF

Detalhes do Exemplar
Número de Chamada: urn:nbn:de:hebis:04-es2022-01557
Data de Publicação: 2022-09-01
Fonte: Erstveröffentlichung: Cook, L.; Sengelmann, M.; Winkler, B.; Nagl, C.; Koch, S.; Schlomann, U.; Slater, E.P.; Miller, M.A.; von Strandmann, E.P.; Dörsam, B.; Preußer, C.; Bartsch, J.W. ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9. Int. J. Mol. Sci. 2022, 23, 1976. https://doi.org/10.3390/ijms23041976
Downloads: 46 (2024), 108 (2023), 22 (2022)
Lizenz: https://creativecommons.org/licenses/by/4.0
Acessar a URL: https://archiv.ub.uni-marburg.de/es/2022/0155
https://doi.org/10.3390/ijms23041976

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