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ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed in tumor and immune cells of the tumor microenvironm...

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Autoren: Cook, Lena, Sengelmann, Marie, Winkler, Birte, Nagl, Constanze, Koch, Sarah, Schlomann, Uwe, Slater, Emily P., Miller, Miles A., von Strandmann, Elke Pogge, Dörsam, Bastian, Preußer, Christian, Bartsch, Jörg W.
Formato: Artigo
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2022
Assuntos:
tumor microenvironment
MMP-9
regulation
Medizin
ADAM8
extracellular vesicles
PDAC
lipocalin 2
Medical sciences Medicine
Acesso em linha:Texto integral em PDF
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Texto integral em PDF

Área/Cota: urn:nbn:de:hebis:04-es2022-01557
Publikationsdatum: 2022-09-01
Fonte: Erstveröffentlichung: Cook, L.; Sengelmann, M.; Winkler, B.; Nagl, C.; Koch, S.; Schlomann, U.; Slater, E.P.; Miller, M.A.; von Strandmann, E.P.; Dörsam, B.; Preußer, C.; Bartsch, J.W. ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9. Int. J. Mol. Sci. 2022, 23, 1976. https://doi.org/10.3390/ijms23041976
Downloads: 13 (2025), 106 (2024), 108 (2023), 22 (2022)
Lizenz: https://creativecommons.org/licenses/by/4.0
Zugangs-URL: https://archiv.ub.uni-marburg.de/es/2022/0155
https://doi.org/10.3390/ijms23041976

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