Insulin nanocomplexes formed by self-assembly from amine-modified poly(vinyl alcohol)-graft-poly(L-Lactide) for non-invasive mucosal delivery: Preparation, characterization and in vivo investigations

In this work biodegradable DEAPA-PVAL-g-PLLA nanocomplexes were investigated as a colloidal peptide carrier system for non-invasive transmucosal insulin delivery. Chapter 1 describes the basic fundamentals of insulin therapy, current status, problems and future trends. The pathogenesis of diabetes m...

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Auteur principal:	Simon, Michael
Autres auteurs:	Kissel, Thomas (Prof. Dr.) (Directeur de thèse)
Format:	Dissertation
Langue:	anglais
Publié:	Philipps-Universität Marburg 2005
Sujets:	Nanopartikel Nasale Applikation Modifizierte Polymere Insulin Nichtinvasive Insulinapplikation Drug Delivery System Therapeutisches System Nanoparticles Diabetes mellitus Modified Polymers Non-invasive Application Medizin Medical sciences Medicine
Accès en ligne:	Texte intégral en PDF
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