Publikationsserver
Die hereditäre hemorrhagische Telangiektasie: Untersuchungen zur Multiorganbeteiligung bei Patienten mit Epistaxis als Leitsymptom
Die hereditäre hämorrhagische Telangiektasie (Morbus Rendu-Osler-Weber) ist ein autosomal-dominant vererbtes vaskuläres Fehlbildungssyndrom. Hierbei werden multiple arteriovenöse Malformationen (AVM) im Bereich der Schleimhaut der oberen Luft- und Speisewege sowie der Haut beobachtet...
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| Awduron Eraill: | |
| Fformat: | Dissertation |
| Iaith: | Almaeneg |
| Cyhoeddwyd: |
Philipps-Universität Marburg
2004
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Occult visceral arterio-venous malformations (AVMs) may be a constant threat to patients suffering from Hereditary, Haemorrhagic Telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome (M. ROW). HHT patients predominantly become symptomatic through chronic, recurrent epistaxis, a symptom, which could alert physicians at an early stage of the disease. The purpose of this study was to investigate, whether occult, visceral arterio-venous malformations could be detected by screening imaging studies in patients suffering from HHT. In a comprehensive diagnostic study Rendu-Osler-Weber patients were examined for potential visceral arterio-venous malformations by physical examination and non-invasive imaging techniques. Conclusions: Comprehensive screening for occult AVMs in HHT patients seems to be justified to avert potential complications in this group of patients.