Deregulation of signal transduction pathways in macrophages by arachidonic acid in the ovarian cancer microenvironment

Malignant ascites contributes to all hallmarks of ovarian cancer (OC). It occurs as an accumulation of fluid in the peritoneal cavity at advanced stages of the disease. Ascites is associated with a poor prognosis along with a deteriorated quality of life due to abdominal distension. It is now well e...

Ausführliche Beschreibung

Bibliographische Detailangaben

1. Verfasser:	Hammoud, Mohamad Khir
Beteiligte:	Müller, Rolf (Prof.Dr.) (BetreuerIn (Doktorarbeit))
Format:	Dissertation
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2022
Schlagworte:	Medizin Macrophages, Tumor microenvironment, Arachidonic acid, TAM, IFNG, IFNB, IL6, Lipid rafts, IL12, ASK1, p38, HSP27, Actin filaments. Medical sciences Medicine
Online-Zugang:	PDF-Volltext
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