Mathematical modelling of metabolism and enzyme-level regulation to understand and infer functional regulators of metabolism

Mathematical modelling of metabolism and enzyme-level regulation to understand and infer functional regulators of metabolism

Der mikrobielle Stoffwechsel ist komplex und wird durch Feedback Regulation auf vielen Ebenen reguliert. Feedback Regulation kann durch Metabolit-Protein Interaktionen ausgeführt werden, die allosterisch Enzymaktivität, oder transkriptionell Enzymmengen regulieren. Diese Regulationsmechanismen erlau...

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Detalhes bibliográficos
Autor principal: Farke, Niklas
Outros Autores: Link, Hannes P. (Prof. Dr.-Ing.) (Orientador)
Formato: Dissertation
Idioma:alemão
Publicado em: Philipps-Universität Marburg 2022
Assuntos:
Feedback Inhibierung
metabolism
feedback regulation
Metabolite
Mathematical modelling
enzyme-level regulation
Escherichia coli
Stoffwechsel
Transkriptionsfaktor
Mathematische Modellierung
Enzymmengen Regulation
Biowissenschaften, Biologie
transcriptional feedback inhibition,
allosteric feedback inhibition
Life sciences
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