The coincidence biosensor tubbyCT reveals local phosphatidylinositol-4,5-bisphosphate synthesis at endoplasmic reticulum-plasma membrane junctions

The coincidence biosensor tubbyCT reveals local phosphatidylinositol-4,5-bisphosphate synthesis at endoplasmic reticulum-plasma membrane junctions

Phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2) plays a prominent role in plasma membrane (PM) physiology. It is implicated in the regulation of a variety of cellular functions including exo- and endocytosis, cytoskeleton anchorage, and ion channel activity. Activation of Gq-coupled receptors indu...

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Detalhes bibliográficos
Autor principal: Thallmair, Veronika
Outros Autores: Oliver, Dominik (Orientador)
Formato: Dissertation
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2020
Assuntos:
phospholipase C
ER-PM junctions
lipid transfer
tubby
Phospholipase C
Lipidbiosensor
phosphoinositides
Tubby
Lipidtransfer
Phosphoinositide
Medizin
membrane contact sites
lipid biosensor
Medical sciences Medicine
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