From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme

From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme

Serendipity has played a historically significant role in science and especially in the discovery of new drugs. Chance discoveries have led to important drug developments that characterize the pharmaceutical industry and our current health care system. Over the last decades, the concept of rational...

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Detalhes bibliográficos
Autor principal: Nguyen, Dzung
Outros Autores: Klebe, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Formato: Dissertation
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2020
Assuntos:
Shigellose
Fragments
Assayentwicklung
El
Homodimer
Assay Development
Wirkstoffdesign
Proteine
Proteindynamik
Proteins
Biowissenschaften, Biologie
Shigellosis
Protein Dynamics
Fragmente
Antibiotics
Protein–Ligand-Wechselwirkung
Drug Design
Protein–Ligand Interaction
Inhibitoren
Inhibitors
Antibiotika
Life sciences
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Detalhes do Exemplar
Área/Cota: urn:nbn:de:hebis:04-z2021-00679
Publikationsdatum: 2021-02-15
Datum der Annahme: 2021-01-15
Downloads: 147 (2024), 192 (2023), 153 (2022), 138 (2021)
Lizenz: https://creativecommons.org/licenses/by-nc-nd/4.0/
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2021/0067
https://doi.org/10.17192/z2021.0067

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