Transforming growth factor-beta targets Formin-like 2 for Angiopoietin-like 4 secretion during the epithelial mesenchymal transition

Transforming growth factor-beta targets Formin-like 2 for Angiopoietin-like 4 secretion during the epithelial mesenchymal transition

Epithelial to Mesenchymal transition (EMT) is a highly dynamic process that plays a crucial role in tumor progression and metastasis. While remodelling of the actin cytoskeleton is a hallmark of EMT, the responsible actin regulating factors are less well understood. Formins are involved in numerous...

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Bibliographic Details
Main Author: Moussi, Christel Jessica
Contributors: Grosse, Robert (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2019
Subjects:
FMNL2
invasion
EMT
Medizin
ANGPTL4
Formine
migration
Krebs
Medical sciences Medicine
Online Access:PDF Full Text
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