Lipodendriplexes: A promising nanocarrier for enhanced nucleic acid delivery

Lipodendriplexes: A promising nanocarrier for enhanced nucleic acid delivery

The main objective of the current study was to developed an optimized system for enhanced nucleic acid delivery with minimum cytotoxicity. For efficient therapeutic gene delivery, PAMAM dendrimer, with ethylenediamine core was chosen due to its biodegradable and non-immunogenic nature. However, the...

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Bibliografske podrobnosti
Glavni avtor: Tariq, Imran
Drugi avtorji: Bakowsky, Udo (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Jezik:angleščina
Izdano: Philipps-Universität Marburg 2019
Teme:
siRNA
3D-Bioprinting
Ex vivo
Zyto
Gentherapie
Lipodendriplexes
Dendriplexe
Lipodendriplexe
Herunterregulierung
Apoptose
Plasmid-DNA
In vivo
PAMAM
Downregulation
Dendriplexes
Liposomes
Pharmakologie, Therapeutik
Plasmid DNA
Apoptosis
Cytot
3D bioprinting
Liposomen
Gene therapy
Pharmacology & therapeutics, prescription drugs
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