Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

CHD4/Mi-2 is a highly conserved ATP-dependent chromatin remodeller. It is essential in processes like transcription regulation, DNA damage response, cell cycle progression, as well as differentiation and development in eukaryotes. It is one of the catalytic components of the NuRD (nucleosome remodel...

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Autor principal: Kovač, Kristina
Altres autors: Brehm, Alexander, (Prof. Dr.) (Assessor de tesis)
Format: Dissertation
Idioma:anglès
Publicat: Philipps-Universität Marburg 2018
Matèries:
chromatin
Chromatin
CHD4
Histone
mutation
Medizin
chromatin remodelling
Tumor
tumour
nucleosome
Mutation
endometrium
Mutation, CHD4, Chromatin-Remodellierung
Gebärmutterschleimhaut
Nukleosom
Medical sciences Medicine
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