Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

CHD4/Mi-2 is a highly conserved ATP-dependent chromatin remodeller. It is essential in processes like transcription regulation, DNA damage response, cell cycle progression, as well as differentiation and development in eukaryotes. It is one of the catalytic components of the NuRD (nucleosome remodel...

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主要作者: Kovač, Kristina
其他作者: Brehm, Alexander, (Prof. Dr.) (BetreuerIn (Doktorarbeit))
格式: Dissertation
語言:英语
出版: Philipps-Universität Marburg 2018
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索引號: urn:nbn:de:hebis:04-z2018-02561
Publikationsdatum: 2018-06-04
Datum der Annahme: 2018-04-24
Downloads: 104 (2024), 117 (2023), 87 (2022), 69 (2021), 67 (2020), 44 (2019), 62 (2018)
Lizenz: https://creativecommons.org/licenses/by-nc-sa/4.0
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2018/0256
https://doi.org/10.17192/z2018.0256