Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

Functional characterisation of cancer-associated mutations in the chromatin remodeler CHD4/dMi-2

CHD4/Mi-2 is a highly conserved ATP-dependent chromatin remodeller. It is essential in processes like transcription regulation, DNA damage response, cell cycle progression, as well as differentiation and development in eukaryotes. It is one of the catalytic components of the NuRD (nucleosome remodel...

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Autore principale: Kovač, Kristina
Altri autori: Brehm, Alexander, (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2018
Soggetti:
chromatin
Chromatin
CHD4
Histone
mutation
Medizin
chromatin remodelling
Tumor
tumour
nucleosome
Mutation
endometrium
Mutation, CHD4, Chromatin-Remodellierung
Gebärmutterschleimhaut
Nukleosom
Medical sciences Medicine
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Collocazione: urn:nbn:de:hebis:04-z2018-02561
Data di pubblicazione: 2018-06-04
Datum der Annahme: 2018-04-24
Downloads: 107 (2024), 117 (2023), 87 (2022), 69 (2021), 67 (2020), 44 (2019), 62 (2018)
Lizenz: https://creativecommons.org/licenses/by-nc-sa/4.0
URL di accesso: https://archiv.ub.uni-marburg.de/diss/z2018/0256
https://doi.org/10.17192/z2018.0256

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