Opposing activities of IRF1 and IRF4 in regulating the Il9 locus in Th9 cells
The T helper (Th)9 cell transcriptional network is formed by an equilibrium of signals induced by cytokines and antigen presentation. Positive regulators including interferon regulatory factor (IRF)4 promote expression of the key cytokine interleukin (IL)-9 in Th9 cells, whereas interferon (IFN)-γ r...
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