Selective targeting of immunoproteasome subunit LMP7 prevents colitis-associated carcinogenesis

Selective targeting of immunoproteasome subunit LMP7 prevents colitis-associated carcinogenesis

Chronic inflammation is a well-known risk factor for the development of colonic tumorigenesis. In this study, we show that the immunoproteasome (iP) subunit LMP7 plays a crucial role in the progression of colitis-associated carcinogenesis (CAC). The activity and function of the iP complex has been e...

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Bibliografske podrobnosti
Glavni avtor: Vachharajani, Niyati
Drugi avtorji: Višekruna, Alexander (PD Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Jezik:angleščina
Izdano: Philipps-Universität Marburg 2016
Teme:
Colitis-associated Carcinogenesis
Medizin
Entzündung
CAC
Colon
Kolon
Colitis-assoziierte Karzinogenese
Inflammation
Medical sciences Medicine
Online dostop:PDF-Volltext
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Internet

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Podrobnosti zaloge
Signatura: urn:nbn:de:hebis:04-z2016-08958
Publikationsdatum: 2016-12-14
Datum der Annahme: 2016-11-14
Downloads: 56 (2024), 121 (2023), 137 (2022), 111 (2021), 62 (2020), 123 (2019), 25 (2018)
Lizenz: https://creativecommons.org/licenses/by-nc-sa/4.0
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2016/0895
https://doi.org/10.17192/z2016.0895

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