Octahedral Chiral-at-Metal Iridium and Rhodium Complexes as Versatile Asymmetric Catalysts
Over the past several years, our group has been interested in designing and synthesizing different novel octahedral chiral-at-metal complexes and their application in asymmetric catalysis, including visible-light-induced asymmetric catalysis. This thesis mainly includes two parts: one is the versa...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Beteiligte: | |
| Format: | Dissertation |
| Sprache: | Englisch |
| Veröffentlicht: |
Philipps-Universität Marburg
2016
|
| Schlagworte: | |
| Online-Zugang: | PDF-Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | Over the past several years, our group has been interested in designing and synthesizing different novel octahedral chiral-at-metal complexes and their application in asymmetric catalysis, including visible-light-induced asymmetric catalysis.
This thesis mainly includes two parts: one is the versatile asymmetric catalysis by octahedral chiral-at-metal iridium complexes, and the other one is the visible-light-promoted asymmetric α-amination by octahedral chiral-at-metal rhodium complex.
In the first part of this thesis, octahedral chiral-at-metal iridium complexes IrS and IrO are used as highly effective chiral Lewis acid catalysts for a variety of asymmetric reactions, including Friedel-Crafts alkylations, Michael additions with CH-acidic compounds, 1,3-dipolar cycloadditions, Diels Alder cycloadditions, hetero Diels Alder cycloadditions and Henry reactions.
In the second part of the thesis, a very efficient photoactivated enantioselective radical amination of 2-acyl imidazoles catalyzed by an octahedral chiral-at-metal rhodium complex RhO is introduced. Rhodium complex here serves a dual function, namely as a chiral Lewis acid to catalyze asymmetric enolate chemistry and furthermore as a light-activated smart initiator of a radical chain process. |
|---|---|
| Umfang: | 315 Seiten |
| DOI: | 10.17192/z2016.0121 |