Functional Characterization of the BCR/JAK2 Fusion Gene in a Murine Pro B Cell Line

Functional Characterization of the BCR/JAK2 Fusion Gene in a Murine Pro B Cell Line

Functional description of the BCR/JAK2 fusion gene, which has been described in a patient suffering from chronic myeloid leukaemia in 2005. The T(translocation)(9;22)(p24;q11.2)leads to the formation of a fusion gene which incorporates critical regions of the breakpoint cluster region- as well as th...

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Bibliographic Details
Main Author: Marbach, Felix
Contributors: Bohlander, Stefan (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2015
Subjects:
Fusion gene
Translokation
Leukämie
Medical applications (general)
Tumor
Klonierung
Fusionsgen
Tyrosine kinase inhibitor
Protein-Tyrosin-Kinasen
Medizin
Onkogen
Tyrosinkinase-Inhibitor
Mutation
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2015-06269
Publication Date: 2015-12-16
Date of Acceptance: 2015-11-02
Downloads: 33 (2024), 51 (2023), 60 (2022), 58 (2021), 54 (2020), 152 (2019), 69 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2015/0626
https://doi.org/10.17192/z2015.0626

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