An extracellular drug binding site of potassium channels THIK-1 and THIK-2

An extracellular drug binding site of potassium channels THIK-1 and THIK-2

Background: THIK-1, THIK-2 and TREK-1 and all belong to family of two-pore-domain potassium channel (K2P channels). THIK-2 was until recently regarded as ‘silent’ potassium channels. 3-isobutyl-1-methylxanthine (IBMX) is normally used as inhibitor of phosphodiesterase, resulting in an increase of cA...

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Bibliographic Details
Main Author: Zou, Xinle
Contributors: Daut, Jürgen (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2015
Subjects:
Kanal, IBMX, THIK
channel
Kalium
IBMX
Medizin
Kanal
potassium
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2015-03314
Publication Date: 2015-07-09
Date of Acceptance: 2015-07-02
Downloads: 50 (2024), 75 (2023), 97 (2022), 91 (2021), 79 (2020), 88 (2019), 77 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2015/0331
https://doi.org/10.17192/z2015.0331

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