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Investigations on lin-Benzopurines With Respect to Dissociation Behavior, Pocket Cross-Talk, Targeting Resistance Mutants, Residual Mobility, and Scaffold Optimization
The present thesis deals with the characterization and improvement of selective antibiotics targeting the enzyme tRNA–guanine transglycosylase. Recently, the lin-benzopurine scaffold was introduced as promising starting point for the structure-based design of TGT inhibitors. Two classes, namely the...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| التنسيق: | Dissertation |
| اللغة: | الإنجليزية |
| منشور في: |
Philipps-Universität Marburg
2014
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| الموضوعات: | |
| الوصول للمادة أونلاين: | PDF النص الكامل |
| الوسوم: |
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