Interaction dynamics between heterotrimeric G-proteins and type V adenylyl cyclase determine sensitivity of effector regulation

The signalling pathway from G-protein-coupled receptors to the second messenger cAMP is present in virtually all cells and of major physiological and pathophysiological importance. The membrane-spanning receptors can easily be targeted by pharmaceutical compounds and therapies to treat diseases like...

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Manylion Llyfryddiaeth

Prif Awdur:	Milde, Markus
Awduron Eraill:	Bünemann, Moritz (Prof. Dr.) (Cynghorydd traethodau ymchwil)
Fformat:	Dissertation
Iaith:	Saesneg
Cyhoeddwyd:	Philipps-Universität Marburg 2013
Pynciau:	Adenylylzyklase interaction adenylyl cyclase cAMP Dynamik G-protein Fluoreszenz-Resonanz-Energie-Transfer Medizin Interaktion G-Protein FRET Medical sciences Medicine
Mynediad Ar-lein:	Testun PDF llawn
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