Interaction dynamics between heterotrimeric G-proteins and type V adenylyl cyclase determine sensitivity of effector regulation

The signalling pathway from G-protein-coupled receptors to the second messenger cAMP is present in virtually all cells and of major physiological and pathophysiological importance. The membrane-spanning receptors can easily be targeted by pharmaceutical compounds and therapies to treat diseases like...

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Dades bibliogràfiques

Autor principal:	Milde, Markus
Altres autors:	Bünemann, Moritz (Prof. Dr.) (Assessor de tesis)
Format:	Dissertation
Idioma:	anglès
Publicat:	Philipps-Universität Marburg 2013
Matèries:	Adenylylzyklase interaction adenylyl cyclase cAMP Dynamik G-protein Fluoreszenz-Resonanz-Energie-Transfer Medizin Interaktion G-Protein FRET Medical sciences Medicine
Accés en línia:	PDF a text complet
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