Interaction dynamics between heterotrimeric G-proteins and type V adenylyl cyclase determine sensitivity of effector regulation

The signalling pathway from G-protein-coupled receptors to the second messenger cAMP is present in virtually all cells and of major physiological and pathophysiological importance. The membrane-spanning receptors can easily be targeted by pharmaceutical compounds and therapies to treat diseases like...

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Bibliografski detalji

Glavni autor:	Milde, Markus
Daljnji autori:	Bünemann, Moritz (Prof. Dr.) (Savjetnik disertacije)
Format:	Dissertation
Jezik:	engleski
Izdano:	Philipps-Universität Marburg 2013
Teme:	Adenylylzyklase interaction adenylyl cyclase cAMP Dynamik G-protein Fluoreszenz-Resonanz-Energie-Transfer Medizin Interaktion G-Protein FRET Medical sciences Medicine
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