Interaction dynamics between heterotrimeric G-proteins and type V adenylyl cyclase determine sensitivity of effector regulation

The signalling pathway from G-protein-coupled receptors to the second messenger cAMP is present in virtually all cells and of major physiological and pathophysiological importance. The membrane-spanning receptors can easily be targeted by pharmaceutical compounds and therapies to treat diseases like...

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Bibliografiska uppgifter

Huvudskapare:	Milde, Markus
Övriga skapare:	Bünemann, Moritz (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Materialtyp:	Dissertation
Språk:	engelska
Publicerad:	Philipps-Universität Marburg 2013
Ämnen:	Adenylylzyklase interaction adenylyl cyclase cAMP Dynamik G-protein Fluoreszenz-Resonanz-Energie-Transfer Medizin Interaktion G-Protein FRET Medical sciences Medicine
Länkar:	PDF-fulltext
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