Investigations into the mechanism of the coenzyme B12 dependent reaction catalyzed by glutamate mutase from Clostridium cochlearium
Aims of this study were the search for inhibitors of the coenzyme B12-dependent glutamate mutase and for insight into the first step of its catalytic mechanism, the homolytic cleavage of the cobalt-carbon bond. Glutamate mutase is composed of two separately isolated protein components S and E2, whic...
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Format: | Dissertation |
Sprache: | Englisch |
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Philipps-Universität Marburg
2012
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